Health Condition 1: M17- Osteoarthritis of knee
Conditions
Interventions
Intervention1: Platelet Rich plasma injection: One dose 5-7 ml of platelet rich plasma will be injected intra articularly in affected knee joint
Control Intervention1: Hyaluronic acid (Hylan polymer A
Sponsors
ESI Institute of Pain Management
Eligibility
Inclusion criteria
Inclusion criteria: 1) Symptom duration for more than 3 months 2) Confirmatory X-ray Diagnosis according to Kellgrenâ?? Lawrence grade 1â??3 within the past 3 months 3) Patients with no other comorbidities
Exclusion criteria
Exclusion criteria: 1) Patient refusal 2) Infection or active wound in the knee area 3) recent history of severe trauma to the knee 4) autoimmune and platelet disorders 5) treatment with anticoagulant and antiplatelet medications 10 days before injection 6) use of NSAIDs 2 days before injection 7) history of knee intra-articular injections of corticosteroids during the past 3 weeks or use of systemic corticosteroids 2 weeks before PRP injections 8) hemoglobin measures of 12g/dL and platelet counts less than 150,000/ml 9) allergy to avian proteins, feathers and egg products or hypersensitivity to hyaluronate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality of life in Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) scoreTimepoint: before the procedure and at 4 week after the intervention | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain in Numeric Rating ScaleTimepoint: before the procedure and at 4 week after the intervention | — |
Countries
India
Contacts
Public ContactDr Subrata Goswami
ESI Institute of Pain Management
Outcome results
None listed