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Pain Science Education in patients with Chronic Knee Pain

Effects of Pain Neuroscience Education on Function in Knee Osteoarthritis with Central Sensitization: A Randomized Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/03/018261
Enrollment
124
Registered
2019-03-26
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M179- Osteoarthritis of knee, unspecified

Interventions

Intervention1: Pain Neuroscience Education: 8 weeks of supervised rehabilitation with a total 12 sessions will be given. Pain Neuroscience Education(PNE) along with exercises will be given with a tot

Sponsors

SOAHS Manipal Academy of Higher Education
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Individuals diagnosed with OA using American College of Rheumatology (ACR) guidelines that described OA based on clinical examination as knee pain in addition to 3 of the following 6 criteria: -more than 50 years of age -less than 30 minutes of morning stiffness -crepitus -bony tenderness -no enlargement, or an absence of palpable warmth -along with radiographic classification of OA knee by Kellegren and Lawrence. Knee pain for more than 3 months Symptoms of hyperalgesia measured using two-point discrimination device vernier caliper NPRS > 3 on walking.

Exclusion criteria

Exclusion criteria: Systemic inflammatory arthritis Intra- articular corticosteriod injection within 6 months A history of hip or knee surgeries Individuals with associated neurological deficits Intention to start or currently participating in lower limb exercise programs

Design outcomes

Primary

MeasureTime frame
6- minute walk test, two- point discrimination using vernier caliperTimepoint: Baseline, at the end of 8th week

Secondary

MeasureTime frame
Central Sensitization Inventory scaleTimepoint: Baseline, at the end of 8th week;Knee Injury and Osteoarthritis Outcome Survey (KOOS)Timepoint: Baseline, at the end of 8th week;Numerical Pain rating ScaleTimepoint: Baseline, at the end of 8th week;Pain Catastrophizing Scale (PCS)Timepoint: Baseline, at the end of 8th week;Quantitative Sensory Testing - Pain Pressure ThresholdTimepoint: Baseline, at the end of 8th week

Countries

India

Contacts

Public ContactPrem V

SOAHS Manipal Academy of Higher Education

karvannan.h@manipal.edu9986565966

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026