Health Condition 1: E669- Obesity, unspecified
Conditions
Interventions
Intervention1: Study Group- Intravenous Dexmedetomidine: Patients will be randomly allocated into two groups Group D and Group P. Group D patients will receive Intravenous infusion of Dexmedetomidine
Sponsors
Dr Divyangna Sapra
Dr Dipti Saxena
Eligibility
Inclusion criteria
Inclusion criteria: 1) American Society of Anaesthesiologists (ASA) Grade II, III 2) Basal Metabolic Index (BMI) >30 3) Patients scheduled for laparoscopic bariatric surgery under general anaesthesia
Exclusion criteria
Exclusion criteria: Patients with 1) Heart Block or severe ventricular dysfunction, 2) Allergy to Alpha 2 adrenergic drugs, 3) hepatic impairment, 4) Hypotension, 5) Bradycardia, 6) pregnancy or breast feeding.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intraoperative propofol requirementTimepoint: This will be assessed at following time points: 1. At time of induction, 2. During the period of maintenance, 3. During total duration of surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraoperative antihypertensive (Nitroglycerine and Labetalol) requirementTimepoint: During total duration of surgery;Intraoperative haemodynamics (Blood pressure- Systolic, Diastolic and Mean, heart rate, peripheral oxygen saturation)Timepoint: These will be assessed at following 9 time points: 1. Prior to induction, 2. After endotracheal intubation, 3. At the time of Gastric calliberation tube (GCT) insertion, 4. At the time of incision, 5. At the time of start of carbo-peritoneum, 6. At the time of reverse Trendelenburg positioning, 7. At the time of carbo-peritoneum release, 8. At the time of repositioning, 9. Immediately after extubation. | — |
Countries
India
Contacts
Public ContactDr Divyangna Sapra
Sri Aurobindo Medical College and PG Institute, Indore
Outcome results
None listed