Comparing two drugs for giving anesthesia and checking ease of mask ventilation

Effect of Etomidate and Propofol on airway mechanics during induction- A prospective randomised trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/03/018197

Enrollment

Registered

2019-03-20

Start date

Unknown

Completion date

Unknown

Last updated

2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N20- Calculus of kidney and ureter Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: PROPOFOL: 1.5mg/kg Intravenously Control Intervention1: ETOMIDATE: 0.3mg/kg Intravenously

Eligibility

Inclusion criteria

Inclusion criteria: ASA Physical status â?? I, II and III Elective surgery General Anesthesia

Exclusion criteria

Exclusion criteria: Pregnancy Pediatric cases Emergency Anticipated difficult mask ventilation and intubation Any diaphragmatic hernia, gastric outlet obstruction, positive pressure contraindicated conditions

Design outcomes

Primary

Measure	Time frame
To assess the airway mechanics during Mask ventilation after induction- comparing Etomidate and Propofol.Timepoint: After giving induction agent Propofol or Etomidate- every 20 seconds for 1min followed by Rocuronium injection assessed every minute for 10 minutes	—

Secondary

Measure	Time frame
To assess the effect of neuromuscular block on airway dynamics, side effects of Etomidate and PropofolTimepoint: After giving induction agent Propofol or Etomidate- every 20 seconds for 1min followed by Rocuronium injection assessed every minute for 10 minutes	—

Countries

India

Contacts

Public ContactDrJ Kavitha

Nizams Institute of Medical Sciences

drkarunya@gmail.com08143769301

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026