A study to compare the pain relieving action of paracetamol injection inpatients after removal of gall bladder for stones (through small holes on the abdominal wall) when given through veins by two different methods upto 24hrs post-operatively

Comparison of analgesic efficacy of continuous intravenous infusion versus intermittent bolus of paracetamol in postoperative pain relief following laparoscopic cholecystectomy : A randomized control trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/03/018186

Enrollment

Registered

2019-03-20

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K801- Calculus of gallbladder with othercholecystitis

Interventions

Intervention1: Infusion paracetamol: Injection Paracetamol 3g (300ml) will be given by continuous intravenous infusion upto first 24 hours post-operatively Control Intervention1: Bolus Paracetamol: In

Eligibility

Inclusion criteria

Inclusion criteria: ASA I and II Elective laparoscopic cholecystectomy patients

Exclusion criteria

Exclusion criteria: Allergy to paracetamol Psychiatric patient Patients on benzodiazepine therapy Deranged liver function test Emergency laparoscopic cholecystectomy patients Alcoholics

Design outcomes

Primary

Measure	Time frame
Reduction in VAS score by 30% in the first 24hours postoperativelyTimepoint: VAS score will be assessed post-operatively at hourly interval for the first 4 hours and then 8 hourly upto 24 hours, or on need basis	—

Secondary

Measure	Time frame
Amount of rescue analgesics required in the first 24 hrs postoperativelyTimepoint: 24 hrs	—

Countries

India

Contacts

Public ContactDr Aparajita Panda

AIIMS, Bhubaneswar

aparajitahota@yahoo.com9438884118

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026