None listed
Conditions
Interventions
Intervention1: commercially available KY jelly applied topically as open label placebo: 3 times application (with 10-15 minutes interval) of 1 Finger Tip unit (approx. 0.5 gm) of commercially availabl
Sponsors
AIIMS New Delhi
Eligibility
Inclusion criteria
Inclusion criteria: 1. Healthy volunteers age between 20-45 years 2. Willing to give informed consent for the study
Exclusion criteria
Exclusion criteria: 1. Any known cardiovascular disease like hypertension, coronary artery disease, and peripheral vascular disease. 2. History of any acute or chronic pain disorders like migraine and arthritis or any chronic disease like diabetes, tuberculosis, epilepsy, asthma, and malignancy. 3. History of an allergic reaction to topical lignocaine application 4. History of drug intake for any disease within the last 1 week 5. External injuries or any skin disease on hands 6. Female subjects should not be a pregnant or nursing mother
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of pain perception as measured by "pain threshold", pain tolerance" (in the form of time) and "pain intensity" (on Visual Analogue Scale) between the open label placebo and double blind placebo group.Timepoint: at the time of enrollment and then next day | — |
Secondary
| Measure | Time frame |
|---|---|
| Comparison of pain perception as measured by "pain threshold", pain tolerance" (in the form of time) and "pain intensity" (on Visual Analogue Scale) among the open label placebo open label treatment, double blind treatment and double blind placebo group.Timepoint: at the time of enrollment and then next day | — |
Countries
India
Contacts
Public ContactShashikant Bhargava
All India Institute of Medical Sciences, New Delhi
Outcome results
None listed