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difference in postoperative nausea and vomiting after ondansetron and granisetron in patient with hysterectomies

A comparative study between ondansetron and granisetron for post operative nausea and vomiting in laproscopic hysterectomies

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/03/018150
Enrollment
160
Registered
2019-03-18
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N939- Abnormal uterine and vaginal bleeding, unspecified

Interventions

Intervention1: granisetron 2mg use as antiemetic agent.: granisetron 2 mg will be given 2 minute prior to induction of anesthesia and effect will be follow up 24 hours post operatively. Control Inter

Sponsors

SDMH
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Females of ASA grade I and II 2. Females of age 18-55 yrs 3. Patient who gives informed written consent 4. Females who are undergoing laproscopic hysterectomies

Exclusion criteria

Exclusion criteria: ASA ââ?°Â¥ grade III 2. Females with major systemic illness 3. Patient with history of PONV in previous surgery 4. Patient with history of vomiting and ryleââ?¬•s tube in situ in last 24 hours 5. Patient with history of allergy to the drug 6. Patient who refuse to give consent 7. Patient having neurological and renal diseases. 8. Pregnant females

Design outcomes

Primary

MeasureTime frame
incidence of post operative nausea and vomitingTimepoint: for 24 hours postoperatively

Secondary

MeasureTime frame
assess demand of rescue antiemetic. compare side effects of ondansetron and granisetronTimepoint: intraoperatively and for 24 hours post operatively

Countries

India

Contacts

Public ContactToshi gupta

Santokba durlabhji memorial hospital

drshobhaparashar@gmail.com9928300078

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026