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Comparison between labetalol and dexmedetomidine infusion for hypotensive anesthesia in middle ear surgery

Comparison between labetalol and dexmedetomidine infusion for hypotensive anesthesia in middle ear surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/03/018088
Enrollment
78
Registered
2019-03-14
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H712- Cholesteatoma of mastoid

Interventions

Intervention1: DEXMEDETOMIDINE INFUSION: After receiving the patients in the operating room, an intravenous line will be established with an 18 G intravenous cannula and infusion of lactated ringerâ??

Sponsors

Institute of Post Graduate Medical Education and Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Randomly selected patients admitted in ENT ward with middle ear pathology belonging to ASA ( American Society of Anesthesiologist) status l or ll and aged from 18 to 60 years of either sex and willing to give consent will be included in the study

Exclusion criteria

Exclusion criteria: Pregnant and breast feeding women Pre-existing cardiac disease ,renal disorder ,hepatic disease and psychiatric disorder Patients refuses to participate. History suggestive of any coagulation disorder H/O Allergy to Drugs History suggestive of operation in same ear Any other contraindications for using labetalol and dexmedetomidine

Design outcomes

Primary

MeasureTime frame
Dexmedetomidine and labetalol infusion both will be effective to induce controlled hypotension in patients undergoing middle ear surgery. However which drug will be more efficient in compare to other to improve bleeding and surgeons satisfaction and lower side effects and provide better surgical field condition will be evaluated.Timepoint: 20/03/2019 to 20/09/2019

Secondary

MeasureTime frame
which drug will be more efficient in compare to other to improve bleeding,surgeons satisfaction, lower side effects, and provide better surgical field condition will be evaluated.Timepoint: 20/03/2019 to 20/09/2019

Countries

India

Contacts

Public ContactDr Purnendu Bikash Pramanik

Institute of Post Graduate Medical Education and Research Institute

purnendu0308@gmail.com9002653848

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026