Health Condition 1: N289- Disorder of kidney and ureter, unspecified
Conditions
Interventions
Intervention1: Dexamethasone: A single injection of 0.15 mg/kg upto a maximum of 5mg of dexamethasone diluted to a total volume of 2ml with 0.9% saline will be given at the time of induction intraveno
Sponsors
Department of Anaesthesiology AIIMS
Eligibility
Inclusion criteria
Inclusion criteria: ASA I and ASA II children undergoing surgery
Exclusion criteria
Exclusion criteria: 1. Patients who had taken a steroid medication within the last 24 h or had received chronic steroid medication or medicines, such as furosemide, magnesium, or cephalosporin, known to influence the neuromuscular function. 2. Patients with neuromuscular disease or hepatic and renal disease. 3. A history of allergy to atracurium and dexamethasone. 4. Severe and significant congenital heart disease. 5. Parental refusal. 6. Weight 7. Suspected difficult airway.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| a) The time in minutes between the start of atracurium injection and 25% twitch height recovery of T1 (clinical duration). b) The time in minutes between 25 and 75% twitch height recovery of T1 (recovery index). c) The time in minutes between the 25% twitch height recovery of T1 and recovery of neuromuscular block to a TOF ratio of 0.9 (recovery time). d) The time between the start of atracurium injection till the recovery of neuromuscular block to a TOF ratio of 0.9 (total recovery time). Timepoint: Time - 0, 25, 75, 90 | — |
Primary
| Measure | Time frame |
|---|---|
| a) Onset time: the time in seconds between the start of atracurium injection and maximum T1 depression b) The incidence of incomplete neuromuscular block (below 95% T1 depression). Timepoint: time - 0 | — |
Countries
Germany
Contacts
Public ContactDr Lokesh Kashyap
AIIMS
Outcome results
None listed