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A study to compare the effect of combination of drugs (ropivacaine with morphine )against other drug combination(ropivacaine with dexemedetomidine) for providing pain relief through a nerve block (paravertebral block) in children operated for lung surgery(decortication)using ultrasound technique

A comparison of Ropivacaine with Morphine versus Ropivacaine with Dexmedetomidine in Ultrasound guided single site paravertebral block in children undergoing Lung decortication - A double blinded randomised controlled trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/03/018072
Enrollment
60
Registered
2019-03-13
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J869- Pyothorax without fistula

Interventions

Intervention1: 0.5 % of 0.3 ml/kg of ropivacaine with 50 ug/kg of morphine (group M): patients will receive ultrasound guided single site paravertebral block at 5th space with 0.3ml/kg of ropivicaine

Sponsors

Amber Rawat
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.) Children in ASA1 and 2 physical health undergoing lung decortication surgery for pyothorax 2.) Parents consenting for participation in the study

Exclusion criteria

Exclusion criteria: 1.) ASA physical status more than 2 . 2.) Parents not consenting for participation in the study. 3.) Allergy to ropivacaine, morphine or dexmedetomidine 4.) Coagulopathy 5.) Local site infection 6.) Renal, hepatic , cardiac or mental dysfunction

Design outcomes

Primary

MeasureTime frame
1.) Haemodynamic stability measured by HR(heart rate) and BP(Blood pressure) 2.) Intensity of pain measured by VAS( Visual Analogue Scale) 2.) Duration of analgesiaTimepoint: HR(heart rate) and BP(Blood pressure) To be measured every 5 minutes during the surgery. 2.) Intensity of pain measured by VAS( Visual Analogue Scale) every 4 hours after surgery completion till first 24 hours after surgery 2.) Duration of analgesia will be evaluated every 4 hours till administration of rescue analgesia

Secondary

MeasureTime frame
1.)Total dose of rescue analgesic (tramadol) consumption in the first 24 hours. 2.) Bradycardia or hypotension 3.) Nausea and vomitingTimepoint: Every 4 hourly from the end of surgery till 1st 24 hours after surgery

Countries

India

Contacts

Public ContactAmber Rawat

institute of medical sciences

amberrawat@gmail.com9598884488

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026