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Benefit of modification of radiotherapy treatment plan at mid treatment for head and neck cancer patients

18F- FDG PET CT based adaptive radiotherapy in pharyngeal and laryngeal cancer patients â?? A study on change in target volumes and reduction in OAR doses

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2019/03/018049
Enrollment
30
Registered
2019-03-12
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C13- Malignant neoplasm of hypopharynx Health Condition 2: C32- Malignant neoplasm of larynx Health Condition 3: C11- Malignant neoplasm of nasopharynx Health Condition 4: C10- Malignant neoplasm of oropharynx

Interventions

Intervention1: Nil: Nil Control Intervention1: Nil: Nil

Sponsors

Basavatrakam Indo American Cancer Hospital and Research Institute Hyderabad
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Histological proven pharyngeal & laryngeal cancer patients 2. ECOG Performance status 0-1 3. Undergoing Definitive chemoradiation 4. Treated with Conformal Radiotherapy techniques

Exclusion criteria

Exclusion criteria: 1. Stage IVB disease 2. ECOG Performance status 2 or more 3. Previous radiation exposure to head and neck 4. Patients who has undergone head and neck surgery / neck dissection 5. Patients who have recurrence

Design outcomes

Primary

MeasureTime frame
To assess reduction in OAR doses with adaptive radiotherapy planTimepoint: 4th week of radiotherapy—

Secondary

MeasureTime frame
To assess volumetric changes in tumor volume and metabolic response based on SUVTimepoint: 4th week of Radiotherapy—

Countries

India

Contacts

Public ContactVinodh Kumar

Basavatrakam Indo American Cancer Hospital and Research Institute, Hyderabad

drakraju@induscancer.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026