Role of dexmedetomidine spary through nasal route on patients comfort and sedation during fiber optic intubation in unstable cervical spine fracture.

Efficacy of atomized intranasal dexmedetomidine on patients comfort and sedation during awake fiber optic intubation in unstable cervical spine fracture -A randomized placebo controlled double blind prospective study.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/03/018027

Enrollment

Registered

2019-03-12

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Intranasal dexmedetomidine: Intranasal dexmedetomidine(2Âµg/kg) will be atomized(total volume 2ml eqivalent) through both nostril Control Intervention1: intranasal NS: equivalent volume

Eligibility

Inclusion criteria

Inclusion criteria: Patient with anticipated difficult airway 1.Unstable cervical spine posted for -elective cervical fixation

Exclusion criteria

Exclusion criteria: 1.Patient having sensitivity to local anesthesia 2.ASA-III &IV 3.Higher degree of A-V Block 4.Obstructive sleep apnea 5.Morbid obesity 6.Patient on ACE inhibitor, alpha antagonist, TCA

Design outcomes

Primary

Measure	Time frame
a)To assess the patientâ??s comfort and sedation through OAA/S score b) comfort score Timepoint: OAA/S score at 10,20 ,30,35,40 min after study drug administration, b) Patientâ??s comfort by 5 points fiberoptic intubation comfort score during AFOI,	—

Secondary

Measure	Time frame
1) haemodynamic alternation, 2) ease of intubation, 3) postoperative recallTimepoint: , Ease of intubation by operator through intubation score during AFOI, Hemodynamic parameters at different time intervals before, during and after AFOI. Postoperative recall 24 hr after operation by 5 point awareness scale.	—

Countries

India

Contacts

Public ContactPROFESSOR DR AMITA ACHARJEE PAHARI

BANGUR INSTITUTE OF NEURO SCIENCES

dr.amitaacharya@yahoo.com9831650768

Outcome results