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To test saliva and compare anti-caries agents for prevention of radiation caries among Head and Neck cancer patients undergoing radiotherapy.

Evaluation of saliva and comparison of anti-caries agents for prevention of radiation caries among Head and Neck cancer patients undergoing radiotherapy - an invivo study.

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/03/017977
Enrollment
150
Registered
2019-03-07
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C148- Malignant neoplasm of overlappingsites of lip, oral cavity and pharynx

Interventions

Intervention1: Evaluation and comparison of anti-caries agents for prevention of radiation caries among Head and Neck cancer patients undergoing radiotherapy.: Three prophylactic agents will be assign

Sponsors

Nitte Deemed to be University
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: -Patients diagnosed with head and neck cancer. - Patients undergoing radiotherapy with IMRT -older than 12 years old age

Exclusion criteria

Exclusion criteria: - Patients not undergoing radiotherapy -stage III and stage IV patients with trismus having restricted mouth opening -patients undergoing surgery -patients undergoing chemotherapy -patients suffering from other systemic conditions -Subjects those who have history of allergy to oil use

Design outcomes

Primary

MeasureTime frame
root caries index (RCI) for each subject will be calculatedTimepoint: To compare the changes in root caries index between the study groups at the 1st week, 6th ,12th and 24th week. (before and after radiotherapy)

Secondary

MeasureTime frame
To compare the quantity and quality of saliva between the study groups using saliva kits.Timepoint: To compare the quantity and quality of saliva between the study groups at the 1st week, 6th ,12th and 24th week.

Countries

India

Contacts

Public ContactUPASANA

A.B.Shetty Institute of Dental Sciences

upasana.reddy.88@gmail.com9845827259

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026