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Measuring the covering layer of nerve comimg from eye ball with the help of ultrasound machine, in patients undergoing spine surgery in normal lying down and upside down position with apllication of positive pressure during ventilation.

The Effect of Positive End-Expiratory Pressure on Sonographic Optic Nerve Sheath Diameter in Patients undergoing Spine surgery in Prone position â?? A Randomized Controlled Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/03/017951
Enrollment
44
Registered
2019-03-06
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G55- Nerve root and plexus compressionsin diseases classified elsewhere

Interventions

Intervention1: Application of Positive End Expiratiry Pressure (PEEP) in Prone Position: In this study group PEEP of 8 will be applied. Optic nerve sheath diameter (ONSD) will be assessed to evaluate

Sponsors

Sir Ganga Ram Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Giving consent for study 2.ASA Physical status I and II 3.Spinal surgery 4.BMI- 18.5 - 27.5 Kilogram/Meter square

Exclusion criteria

Exclusion criteria: 1.Inability to obtain informed consent 2.History of ocular(posterior segment) or intracranial surgery 3.Pre-existing intracranial/pulmonary pathology 4.History of hypersensitivity to anaesthetic dugs. 1.Patient refusal 2.History of ocular or cranial surgery 3.Pre existing pulmonary diseade 4.History of bradyarrythmias 5.Patient on beta blockers

Design outcomes

Primary

MeasureTime frame
Optic nerve sheath diameter pre surgery in supine position and then in prone position after application of the allocated PEEP settingTimepoint: 1. 15 minutes after induction in supine position 2. 15 minutes after applying the allocated PEEP setting in prone position

Secondary

MeasureTime frame
1.Mean airway pressure 2.HemodynamicsTimepoint: Every 15 min after induction of anaesthesia

Countries

India

Contacts

Public ContactDr Rachna Bhutani

Sir Ganga Ram Hospital

rachnabhutani@ymail.com01142252523

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026