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Comparison between two doses of Dexmedetomidine through Epidural Infusion for Post-operative Pain Relief

Comparison Between Two Different Doses of Dexmedetomidine through Continuous Epidural Infusion For Postoperative Analgesic Efficacy And Safety in Lower Limb Surgeries â?? Prospective Randomized Double-Blind Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/03/017895
Enrollment
72
Registered
2019-03-01
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M96-M96- Intraoperative and postprocedural complications and disorders of musculoskeletal system, not elsewhere classified

Interventions

Intervention1: Dexmedetomidine: Postoperative Continuous Epidural Infusion for analgesia Divided into two groups: �Group 1 will receive Epidural Infusion 0.1% Ropivacaine + 0.5µg/kg/24hours of De

Sponsors

Sam Blessy Sheba
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients of both sex undergoing lower limb surgeries under Combined Spinal and Epidural Anaesthesia (CSEA) willing to be included in the study

Exclusion criteria

Exclusion criteria: 1.Patients with Cardiac pathology 2.Hypertension 3.BMI 30 kg/m2 4.Known allergy to local anaesthetic infiltration 5.Chronic use of any other analgesics 6.American Society of Anaesthesiologists (ASA) III and above 7.Pregnant patients 8.Refusal for consent

Design outcomes

Primary

MeasureTime frame
To compare analgesic efficacy in terms of Pain Scores in the first 24 hours postoperatively. Timepoint: To compare analgesic efficacy in terms of Pain Scores in the first 24 hours postoperatively.—

Secondary

MeasureTime frame
â?¢To compare safety profile measured by sedation score and hemodynamic parameters up to 48 hours post operatively â?¢To compare pain scores in the next 24 hours, up to 48 hours postoperatively Timepoint: Postoperatively Postoperatively—

Countries

India

Contacts

Public ContactSam Blessy Sheba

Sri Balaji Vidyapeeth

pranjalikurhekar@gmail.com9486414942

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026