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The effects of tracheal tube cuffs filled with air, saline or alkalinised lidocaine (a local anaesthetic) on heart rate and blood pressure upon removal of tracheal tube and on cough, hoarseness of voice and sore throat in postoperative period in children.

Comparative evaluation of tracheal tube cuff filled with air, saline or alkalinised lidocaine on laryngotracheal morbidity and haemodynamic changes in children.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/02/017871
Enrollment
45
Registered
2019-02-28
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Air, saline, alkalinised lidocaine: Tracheal tube cuff is filled with one of the following - air or saline or alkalinised lidocaine. Control Intervention1: Not applicable: Not applicabl

Sponsors

Department of Anaesthesiology
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA physical status grade 1 or 2. Children planned for elective surgery and requiring general anaesthesia with orotracheal intubation. Surgeries expected to last 1-3 hours.

Exclusion criteria

Exclusion criteria: Children with oropharyngeal or neck malformations. Children who had previously required tracheal intubation or tracheostomy. Presence of stridor or dysphonia. Children requiring surgery of neck, larynx or oropharynx. Children requiring a nasogastric or orogastric tube. Children requiring or receiving steroid medication.

Design outcomes

Primary

MeasureTime frame
Laryngotracheal morbidity i.e. Cough Hoarseness of voice Sore throatTimepoint: 1 hour and 6 hours following tracheal extubation—

Secondary

MeasureTime frame
Haemodynamic changes i.e. Systolic blood pressure Diastolic blood pressure Heart rate The difference between the highest of 3 readings at following (a) and (b) time points is considered.Timepoint: Three times at two minutes interval (a) before administration of neuromuscular blockade reversal agents and (b) after tracheal extubation.—

Countries

India

Contacts

Public ContactDr J S Dali

Department of Anaesthesiology, Maulana Azad Medical College

dr_dali@rediffmail.com09818032649

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026