Skip to content

To know which drug out of the two ( morphine and burprenorphine) used for spinal anesthesia has better pain relief in patients after surgeries of below the umblicus

Comparative effects of Buprenorphine and Morphine as adjuvants to Bupivacaine spinal anesthesia in patients undergoing infra-umbilical surgeries - A Prospective study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/02/017811
Enrollment
60
Registered
2019-02-25
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G890- Central pain syndrome

Interventions

Intervention1: Group M: 2.8ml of 0.5%heavy bupivacaine with 100 mcg of morphine intrathecal Intervention2: Group B: 2.8ml of 0.5% heavy bupivacaine with 60 mcg buprenorphine intrathecally Control Inte

Sponsors

Sri Ramakrishna hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA Physical status 1 or 2 Presenting for infraumblical surgeries Patients who provide consent for the study

Exclusion criteria

Exclusion criteria: Patient allergic to the drug ASA Physical status 3 and above , acute or chronic respiratory disease, cognitive or psychiatric disturbances Any contraindication to subarachnoid block Pregnant women Day care procedures Patients who do not give consent

Design outcomes

Primary

MeasureTime frame
To compare the duration of postoperative analgesia of buprenorphine and morphine when given intrathecally with hyperbaric bupivacaineTimepoint: 2, 4, 8, 12, 24 hours of postoperative analgesia

Secondary

MeasureTime frame
Time taken to achieve maximum sensory and motor block Intraoperative hemodynamic changes like bradycardia and hypotension and intraoperative side effects like nausea, vomiting and pruritisTimepoint: Sensory and motor block will be assessed every 2 minutes till maximum level is reached

Countries

India

Contacts

Public ContactHemamalini Arun

Sri Ramakrishna hospital , Coimbatore

prabhadr01@gmail.com9791346959

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026