Health Condition 1: G404- Other generalized epilepsy and epileptic syndromes
Conditions
Interventions
Intervention1: Intravenous Methyl prednisolone (30 mg/kg) plus AEDs: Pulse IV Methyl prednisolone (30mg/kg) will be given for 5 days/ month for 3 months for children who satisfy the inclusion criteria
Sponsors
NON FUNDED NIMHANS
Eligibility
Inclusion criteria
Inclusion criteria: 1) Children with age > 6months 2) Diagnosed as epileptic encephalopathy 3) Negative for basic pediatric neurometabolic work 4) No contraindication for steroid treatment 5) Parents who are willing to participate
Exclusion criteria
Exclusion criteria: 1) Parents who are not willing to participate 2) Who have contraindication to steroids (Recurrent infections, primary or secondary immunodeficiency) 3) West syndrome 4) Age 5) Developmental encephalopathies 6) Patients who have had a trial of steroids in the past
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assessment of seizure control in patients receiving pulse methylprednisoloneTimepoint: 6months | — |
Secondary
| Measure | Time frame |
|---|---|
| a)To study the phenotypic and EEG features of epileptic encephalopathy and correlate it with the seizure control in children with epileptic encephalopathy b) To study the adverse effects of steroidsTimepoint: 6 months | — |
Countries
India
Contacts
Public ContactSanjib sinha
NIMHANS
Outcome results
None listed