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To compare two drugs Dexmeditomidine and mangnesium sulphate in epidural anesthesia in major lower limb orthopaedic surgery

Comparative study of DEXMEDETOMIDINE and Magnesium Sulphate used as an adjuvant to epidural bupivacaine in patients undergoing major lower limb orthopaedic surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/02/017780
Enrollment
80
Registered
2019-02-22
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Dr. Veena Mathur: Senior Professor department of Anaesthesia Jln medical college Ajmer Intervention2: DEXMEDETOMIDINE: epidural anesthesia Control Intervention1: Dr. Kushank sharma: Res

Sponsors

Jln medical college Ajmer
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Age group between 18 years to 65 years. Patients belonging to ASA (American Society of Anaesthesiologists) grade-I and grade-II. Patient free from any associated acute or chronic systemic illness.

Exclusion criteria

Exclusion criteria: Patients not willing to participate in the study. Local sepsis Spinal deformities. Severe systemic disease and neurological disorders. Previous spinal surgeries. Less than 18 years of age or more than 65 years of age. ASA grade III or more. History of coagulopathy. Allergy to study drugs.

Design outcomes

Primary

MeasureTime frame
1.To assess and compare the onset, duration and highest grade of sensory block. 2.To assess and compare the onset, duration and highest grade of motor block. 3.To assess and compare the total duration of effective analgesia by visual analog scale (VAS).Timepoint: Duration of study is around 1 year

Secondary

MeasureTime frame
1.To assess and compare the hemodynamic changes if any. 2.To assess and compare the proportion of patient having adverse effects and any other complications. 3.To assess and compare the peri-operative sedation.Timepoint: Duration of study is around 1 year

Countries

India

Contacts

Public ContactDr Veena mathur

Jln medical college Ajmer

veenamathur41@gmail.com9460517947

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026