Health Condition 1: E101- Type 1 diabetes mellitus with ketoacidosis
Conditions
Interventions
Intervention1: Ringers Lactate: Intravenous fluid therapy based on percentage of assumed dehydration and maintenance
Control Intervention1: Normal Saline: Intravenous fluid therapy based on percentage
Sponsors
Dr Devanshi Singhal
Eligibility
Inclusion criteria
Inclusion criteria: Case definition for diabetic ketoacidosis has been taken as random blood glucose more than 200mg/dL, venous pH less than 7.3 or serum bicarbonate less than 15mmol/L and blood ketones more than or equal to 3mmol/L or moderate or large ketonuria
Exclusion criteria
Exclusion criteria: Children who have received partial treatment or fluid boluses from outside Children with serum sodium less than 135 mEq/L Children with serum potassium more than 5.5 mEq/L
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time taken to achieve resolution of acidosis ie pH more than or equal to 7.3 in both groupsTimepoint: Time taken to achieve resolution of acidosis ie pH more than or equal to 7.3 in both groups | — |
Secondary
| Measure | Time frame |
|---|---|
| Proportion of patients developing acute renal injuryTimepoint: 48 hours;Time taken for normalization of anion gap and blood glucoseTimepoint: 48 hours;Time taken to change type of fluidTimepoint: 48 hours;Total amount of fluid and insulin administeredTimepoint: 48 hours;Total length of stay in PICUTimepoint: 4 days;Total length of stay in the hospitalTimepoint: 2 weeks | — |
Countries
India
Contacts
Public ContactDr Devanshi Singhal
Lady Hardinge Medical College and Associated Hospitals
Outcome results
None listed