FindTrial
Sign In

Effect of vitamin C intake on lung functions in 35 or more than 35 years of age persons

Effect of ascorbic acid supplementation on pulmonary functions in persons of age equal to or more than 35 years: A randomized controlled pilot study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/02/017698
Enrollment
60
Registered
2019-02-18
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Ascorbic acid: 250 mg per-oral once daily for 6 weeks Intervention2: Ascorbic acid: 500 mg per-oral daily in two equally divided doses, for 6 weeks Control Intervention1: No interventio

Sponsors

Vikas Maharshi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: (1) Age > 35 years and (2) Either gender (3) Agreeing to give informed consent

Exclusion criteria

Exclusion criteria: Participants with (1) History of conditions that contraindicates spirometry like hemoptysis, Pneumothorax, recent myocardial infarction, pulmonary embolism & thoracic/abdominal/ocular surgical procedure (within past 3 months), aneurysm (cerebral, abdominal, thoracic), glaucoma, undiagnosed hypertension (2) History of acute/chronic condition affecting the performance (nausea/vomiting, any painful condition affecting mouth, facial palsy etc.) of spirometry (3) History of current infectious airway disease(s) including upper/lower respiratory tract infection and pulmonary tuberculosis (4) History of acute exacerbation of asthma and/or COPD (5) History of smoking in the past 3 month (6) Body mass index > 30 kg/m2 (7) Pregnancy (8) History of taking antioxidant medicine supplementation at least for last 15 days (9) History of daily intake of Amla fruit/its derivative(s) or citrus fruits in an amount accounting daily vitamin C consumption >60 mg, at least for previous 15 days (10) History of taking medications interfering with absorption or action of vitamin C (11) History of allergy with food/drug containing vitamin C

Design outcomes

Primary

MeasureTime frame
Change in pulmonary functionsTimepoint: At baseline and at 6 weeks—

Secondary

MeasureTime frame
1. To compare the change in lung functions after 6 weeks of ascorbic acid supplementation between persons with reduced lung functions and normal lung functions at the baseline. 2. To find optimum dose of daily ascorbic acid supplementation to improve lung functions in persons of age 35 years. Timepoint: At baseline and at 6 weeks—

Countries

India

Contacts

Public ContactVikas Maharshi

All India Institute of Medical Sciences, New Delhi

vikas.maharshi81@gmail.com8368035562

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026