Health Condition 1: M179- Osteoarthritis of knee, unspecified
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Kellegren and Lawrence grade 3 and 4 2. Intact knee ligaments by clinical tests 3. At least 120 degrees of knee flexion 4. Body Mass Index less than 35
Exclusion criteria
Exclusion criteria: 1. Contraindications to MRI 2. Inflammatory arthritis 3. Post traumatic arthritis 4. Complete absence of joint space on radiographs 5. History of past surgeries in the knee concerned 6. Present or past infection in the knee concerned 7. Any intervention to the knee concerned like injection of steroids 8. Coronal plane deformity (varus / valgus) more than 10 degrees 9. Fixed flexion deformity more than 10 degrees 10. Any evidence of knee instability 11. Primary patellofemoral arthritis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Knee functional scoresTimepoint: Pretreatment and 3.6 and 12 months from treatment | — |
Secondary
| Measure | Time frame |
|---|---|
| MRI parameters (cartilage thickness)Timepoint: Pretreatment and 12 months from intervention;Quality of life parametersTimepoint: Pretreatment and 12 months from intervention;Radiological parameters (Joint space width)Timepoint: Pretreatment and 12 months from intervention | — |
Countries
India
Contacts
Sri Sathya Sai Institute of Higher Medical Sciences - Prasanthigram