Health Condition 1: P742- Disturbances of sodium balance ofnewborn
Conditions
Interventions
Intervention1: Non inferiority comparison of number of babies having safe decline in serum sodium between 2 groups: Newborns with hypernatremia will be grouped into two with one group receiving feeds
Sponsors
Dr Shrinidhi K
Eligibility
Inclusion criteria
Inclusion criteria: 1)singleton baby,2)gestational age more than or equal to 36 weeks,3) birth weight 2000 to 5000 grams,4)postnatal age less than or equal to 7 days,5)roomed in with the mother for atleast 48hours for breastfeeding,6)serum sodium 150 to 155 mEq per litre
Exclusion criteria
Exclusion criteria: 1)congenital anomaly which may interfere with adequate oral feed intake,2)culture proven sepsis,3) NICU stay for more than 24 hours,4)IV fluid therapy in prior occasion, 5) endocrine, metabolic, renal or any systemic illness which may cause fluid and electrolyte abnormality
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Non inferiority comparison of the number of babies having safe decline in serum sodium between the two groupsTimepoint: 2 years | — |
Secondary
| Measure | Time frame |
|---|---|
| complications during treatment like feed intolerance, extravasation or thrombophlebitis, altered mental status,seizures,focal neurological deficitTimepoint: 1 week;duration of treatment and duration of hospital stayTimepoint: variable;Percentage of weight gain at the end of treatmentTimepoint: 1 week;superiority comparison of the volume of IV fluids and or feeds requiredTimepoint: 1 week;treatment failureTimepoint: 1 week | — |
Countries
India
Contacts
Public ContactDr K Neelakandan
The Tamilnadu Dr.MGR Medical University
Outcome results
None listed