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Comparison of two drugs used for better surgical outcome and shorter postoperative stay in hospital in patients undergoing nasal surgery.

The efficacy of Dexmedetomidine versus Clonidine for controlled hypotension in functional endoscopic sinus surgery: An observational study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2019/02/017662
Enrollment
200
Registered
2019-02-14
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J329- Chronic sinusitis, unspecified

Interventions

Intervention1: Infusion Dexmedetomidine: IV Dexmedetomidine 1µg/kg (Group D) diluted in 100ml normal saline is given over 15 minutes prior to anaesthetic induction. Control Intervention1: Infusion Cl

Sponsors

Dr Nita Varghese
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: American Society of Anesthesiologists physical status (ASAPS) I and II patients scheduled for elective Functional Endoscopic Sinus Surgery (FESS) under general anaesthesia with controlled ventilation.

Exclusion criteria

Exclusion criteria: Known allergy to Dexmedotimidine and/or Clonidine. Patients with hypertension, bilateral ethmoidal polyp, bilateral extensive sinusitis, significant neurological, psychiatric, liver and kidney disease.

Design outcomes

Primary

MeasureTime frame
Comparison of the reduction of intraoperative blood loss.Timepoint: Baseline preoperatively, every 5 minutes till half an hour of surgery, followed by every 10 minutes till end of surgery.—

Secondary

MeasureTime frame
Provision of a dry operating field, reducing PACU and hospital stay.Timepoint: Baseline preoperatively, every 5 minutes till half an hour of surgery, followed by every 10 minutes till end of surgery. Follow up in post operative ICU.—

Countries

India

Contacts

Public ContactDr Tirth Nayan Vasa

Kasturba Medical College, Manipal Academy of Higher Education (MAHE), Manipal

nitavarghese@gmail.com9901729764

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026