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Stem cells in neonate after delayed cord clamping and umbilical cord milking

Stem cells per ml of blood in neonate after delayed cord clamping and umbilical cord milking

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/02/017656
Enrollment
100
Registered
2019-02-14
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Umbilical cord milking: Intervention: Envelop for the intervention will be opened after obtaining informed consent from the mother/ care taker before mother is in active labour. Delaye

Sponsors

DST
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All inborn neonates born via vaginal route, with gestation age >=37 weeks ie term neonate, has cried immediately after birth and has good muscle tone. Infants born on working days, between 9AM-4 PM will be enrolled so that sample for CD 34+ cells is immediately transferred to lab at 4 °C temperature

Exclusion criteria

Exclusion criteria: Major congenital malformations Caesarean delivery Indirect Coombâ??s test positive Refusal of consent Any high-risk pregnancy e.g.: Baby limp at birth needing resuscitation, history of intrapartum foetal distress, twins, eclampsia, meconium stained liquor with limp baby, gestation diabetes mellitus, maternal seizures, cord prolapsed, avulsed, placenta previa or abruption.

Design outcomes

Primary

MeasureTime frame
Hematopoietic stem cells/ml of blood, in Delayed cord clamping at 60 seconds after birth Hematopoietic stem cells/ml of blood, in umbilical cord milking done within 20 seconds after birth Timepoint: Hematopoietic stem cells/ml of blood, in Delayed cord clamping at 60 seconds after birth Hematopoietic stem cells/ml of blood, in umbilical cord milking done within 20 seconds after birth

Secondary

MeasureTime frame
Duration of third stage of labour, postpartum haemorrhage with volume of blood loss Placental residual blood volume in DCC vs UCM Haematocrit of neonate at 2 hours of life Incidence of respiratory distress, neonatal jaundice and polycythaemia in neonate Outcome of neonate at discharge from hospital Timepoint: At discharge from hospital

Countries

India

Contacts

Public ContactSuksham Jain

Government

dr.sukshamj@gmail.com9988901596

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026