To develop the X-ray dose reduction strategies by developing a new protocol and to test the effect of the strategies on the radiation dose and image quality in computed tomography examination of blood vessels.

Development and testing of dose reduction strategies on radiation dose and image quality in CT angiography.

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/02/017593

Enrollment

228

Registered

2019-02-12

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I671- Cerebral aneurysm, nonruptured Health Condition 2: I743- Embolism and thrombosis of arteries of the lower extremities Health Condition 3: I742- Embolism and thrombosis of arteries of the upper extremities Health Condition 4: I748- Embolism and thrombosis of other arteries

Interventions

Intervention1: Low dose protocol: For Cerebral Angiography three combination of kVp and mAs will be used : 120 kVp with 200 mAs, 100 kVp with 230 mAs, 80 kVp with 260 mAs. For Pulmonary angiography,

Eligibility

Inclusion criteria

Inclusion criteria: Adult patient with age 18 years and above Patients who are willing to participate in the study by signing informed consent

Exclusion criteria

Exclusion criteria: Trauma patient with a fractured leg for CT lower limb angiography. Amputed limb for CT lower and upper limb angiography. Trauma patient with cervical collar for CT cerebral angiography. Neuromuscular disorder

Design outcomes

Primary

Measure	Time frame
Volumetric Computed Tomography Dose Index and Dose Length Product are the DRL quantities suggested by the guidelines. Effective Dose will be calculated by multiplying Dose length product with the region specific conversion factor. The diagnostic reference level value obtained in this study can be used to establish National diagnostic reference levels. Timepoint: Upon completion of the study	—

Secondary

Measure	Time frame
Image quality Analysis and typical value to establish diagnostic reference levelTimepoint: Upon completion of the study	—

Countries

India

Contacts

Public ContactSuresh Sukumar

School of Allied Health Sciences

abhimanyu.pradhan@manipal.edu8088526491

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026