Health Condition 1: K802- Calculus of gallbladder without cholecystitis Health Condition 2: K802- Calculus of gallbladder without cholecystitis
Conditions
Interventions
Intervention1: Dexamethasone Paracetamol: Dexamethasone 8mg will be given nebulised or intravenous with paracetamol 1g intravenous before anaesthesia induction for 15 min
Control Intervention1: IV Par
Sponsors
Safdarjung Hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients fulfilling the criteria of American Society of Anesthesiologists Physical Status I and II adults 2. scheduled for elective laparoscopic cholecystectomy under general anaesthesia with tracheal intubation. 3. Either gender, aged 18-65 years
Exclusion criteria
Exclusion criteria: 1. Patients with a history of recent respiratory tract infection or sore throat within 2. Patients with anticipated difficult intubation 3. Patients receiving analgesic or steroid therapy or known allergy to study drugs 4. Patients with diabetes, obesity, cardiac, respiratory, hepatic or renal disease 5. Pregnant women 6. Surgery duration greater than 3 hours
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the incidence of postoperative sore throat in patients receiving preoperative intravenous paracetamol and a combination of paracetamol with nebulised or intravenous dexamethasoneTimepoint: At recovery 0,1, 6, 12 and 24 hours postoperatively | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To compare the severity of postoperative sore throat among the three groups. 2. To compare the incidence of hoarseness of voice and cough among the groups. Timepoint: At recovery 0,1, 6, 12 and 24 hours postoperatively | — |
Countries
India
Contacts
Public ContactSmita Prakash
Vardhman Mahavir Medical College and Safdarjung Hospital
Outcome results
None listed