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adapted enhanced recovery after surgery pathway vs. standard care in patients undergoing emergency laparotomy for perforation peritonitis- Which is better?

Comparison of adapted enhanced recovery after surgery pathway vs. standard care in patients undergoing emergency laparotomy for perforation peritonitis- A Randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/02/017537
Enrollment
120
Registered
2019-02-07
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K650- Generalized (acute) peritonitis

Interventions

Intervention1: Adapted ERAS pathway: Adapted ERAS (Enhanced recovery after surgery) pathway will be applied to the study group Control Intervention1: Control Group: standard treatment protocol of the

Sponsors

Jawaharlal Institute of Postgraduate Medical Education Research Government of India
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All consecutive patients above 18 years of age, who present to the emergency surgical team with perforation peritonitis, diagnosed based on clinical examination and adjunct investigations and planned for emergency laparotomy after volume resuscitation.

Exclusion criteria

Exclusion criteria: 1.Age less than 18 years 2. Uncontrolled comorbid diseases. 3. Localized peritonitis 4. American Society of Anesthesiologists physical status class 4E 5. Patients with coagulopathy (INR .1.5 and platelet count 6. Patients on vasopressor or ventilator support 7. Septic shock 8. Associated psychiatric or neurological illnesses 9. Pregnant patients 10. Polytrauma patients with associated other intraabdominal organ injury

Design outcomes

Primary

MeasureTime frame
Lenth of hospital stayTimepoint: from 4 days upto 2-3 weeks

Secondary

MeasureTime frame
Time elapsed until resumption of oral feeding ï?· Time for removal of nasogastric tube, drains and catheter ï?· Duration of ileus ï?· Need for extra analgesics ï?· Need for reinsertion of nasogastric tube ï?· Re-admission, re-operation and mortality rate ï?· Medical complications- pulmonary complications, acute renal failure and urinary tract infections. ï?· Surgical complications- incidence of post-operative nausea and vomiting, SSITimepoint: from 1 day upto 2-3 weeks;To identify risk factors which are responsible for delayed discharge/ failure of ERASTimepoint: from 4 days upto 2-3 weeks

Countries

India

Contacts

Public ContactVikram Kate

JIPMER

drvikramkate@gmail.com9843058013

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 20, 2026