Health Condition 1: E660- Obesity due to excess calories Health Condition 2: E119- Type 2 diabetes mellitus without complications
Conditions
Interventions
Control Intervention1: Apelin: Apelin, a novel
bioactive peptide, was found to be positively correlated with obesity and type 2 diabetes mellitus. It plays a certain role in inflammation-related disea
Sponsors
Panineeya institute of dental sciences and research centre
Eligibility
Inclusion criteria
Inclusion criteria: Patients with BMI 30.0 â?? 39.0 kg/m2 for group 2. (Centers for Disease Control and Prevention) Patients previously diagnosed with T2DM and under medication were confirmed by their glycated haemoglobin (HbA1c: 6.5% - 8.5 --ADA,2017) Patients with at least 15 natural teeth remaining. Patients suffering from chronic periodontitis (>= 5mm pocket depth or >= 3mm loss of attachment) were selected. (Update to 1999 Disease Classification-AAP) Patients who have not received periodontal therapy, within preceding six months.
Exclusion criteria
Exclusion criteria: Patients having aggressive periodontitis. Patients having any other systemic diseases. Patients with BMI > 40 kg/m2. Patients with HbA1c > 8.5%. Patients taking high-dose steroid therapy, radiation or immunosuppressive therapy. Pregnant and lactating woman. History of smoking within the past five years. Mentally retarded and un-cooperative patients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| serum and salivary apelin levelsTimepoint: baseline | — |
Secondary
| Measure | Time frame |
|---|---|
| no secondary outcomesTimepoint: not applicable | — |
Countries
India
Contacts
Public ContactDuddukuri Hema
Panineeya institute of dental sciences and research centre
Outcome results
None listed