Comparison of the pain relief with the addition of clonidine along with bupivacaine in ultrasound-guided rectus sheath block in patients undergoing midline incisional hernia repair

Randomized double-blind Comparison of the analgesic efficacy of clonidine with bupivacaine versus bupivacaine alone in ultrasound-guided rectus sheath block for midline incisional hernia repair

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/02/017496

Enrollment

Registered

2019-02-06

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: - Health Condition 3: - Health Condition 4: K429- Umbilical hernia without obstruction or gangrene

Interventions

Intervention1: Group - BC: Rectus sheath block with 8 ml of bupivacaine hydrochloride 0.25% + 1Âµg/kg clonidine in 2ml saline 0.9% administered bilaterally (total dose of clonidine - 2Âµg/kg) Control

Eligibility

Inclusion criteria

Inclusion criteria: • Patients of ASA class I or II undergoing midline incisional hernia repair under general anaesthesia

Exclusion criteria

Exclusion criteria: Morbid obesity (BMI>= 35kg/m2) Significant cardiac, hepatic or renal disease Local infection at site of block Pre-existing coagulation disorder

Design outcomes

Primary

Measure	Time frame
The Time to first request of analgesiaTimepoint: The Time to first request of analgesia	—

Secondary

Measure	Time frame
â?¢ VAS scoreTimepoint: at every 30 minutes for 2 hours at the end of 4th, 6th, 12th, and 24th hours;Total tramadol consumptionTimepoint: At the end of 24 hours	—

Countries

India

Contacts

Public ContactDr Geetanjali T Chilkoti

University College of Medical Sciences

maurya3193@gmail.com8439023216

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026