Health Condition 1: K053- Chronic periodontitis
Conditions
Interventions
Intervention1: FIBRIN GLUE: On the test side the periodontal flap will be approximated on the test site using autologous fibrin glue on the under surface of the raised flap up to
Sponsors
Dr Neha Pradhan
Eligibility
Inclusion criteria
Inclusion criteria: Patients diagnosed with periodontitis, with good systemic health and presence of a minimum of 3 teeth with periodontal pocket depth (PPD) of >=6mm and clinical attachment level (CAL) of >=5mm (stage 3 periodontitis as described by the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Condition and published by the American Academy of Periodontology) in at least two quadrants will be selected.
Exclusion criteria
Exclusion criteria: 1. Patients who have undergone periodontal therapy during the previous 6 months, or exhibit poor plaque control after phase I therapy. 2. History of any systemic disease such as diabetes mellitus, hypertension, osteoporosis, unstable or life-threatening conditions, bleeding disorder, undergoing antibiotic or other antimicrobial therapy. 3. Patients on drugs like aspirin, blood thinners and anticoagulant therapy 4. Patients with history of allergy 5. Current or former smokers. 6. Mobility of selected teeth. 7. Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cytokines Parameter for Interleukin 1-β will be assessed in GCF using a commercially available Enzyme-linked immunosorbent assay kit (ELISA), specific for human IL-1 βTimepoint: baseline 7th day after treatment | — |
Secondary
| Measure | Time frame |
|---|---|
| VAS Score by Freyd in 1923 Timepoint: baseline 7th day 14th day 21st day 28th day;Early Wound Healing Index by Watchel et al in 2005 Timepoint: baseline 7th day 14th day 21st day 28th day;Gingival Index by Loe and Silness in 1963 Timepoint: baseline 7th day 14th day 21st day 28th day;Oral Hygiene Index by John C Greene and Jack R Vermilion in 1964 Timepoint: baseline 7th day 14th day 21st day 28th day | — |
Countries
India
Contacts
Public ContactDr Sphoorthi A Belludi
KLE Societys Institute of Dental Sciences
Outcome results
None listed