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Outcomes following emergency surgery for patients with head injury

Global Neurotrauma Outcomes Study (GNOS) - outcomes following emergency surgery for traumatic brain injury, a multi-centre, international, prospective cohort study - GNOS

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2019/02/017479
Enrollment
356
Registered
2019-02-05
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G89-G99- Other disorders of the nervous system Health Condition 2: S068- Other specified intracranial injuries

Interventions

None listed

Sponsors

National Institute for Health Research NIHR
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Hospital inclusion criteria Any hospital or clinic worldwide performing emergency surgery for traumatic brain injury is eligible to participate. NIMHANS complies to this criterion fully. Core Study patient inclusion and exclusion criteria Inclusion criteria All adult and paediatric patients admitted to NIMHANS with a traumatic brain injury for which they receive emergency surgery during the selected 30-day inclusion period are eligible for inclusion in the core study.

Exclusion criteria

Exclusion criteria: Patients who only have an external ventricular drain or intraparenchymal wire (or other monitoring device) inserted for the diagnosis and/or management of intracranial hypertension. ï?· Patients who undergo procedures for chronic subdural haematoma(s), including burr holes or mini-craniotomies. ï?· Elective (planned admission) or semi-elective (where patient initially admitted as an emergency, then discharged from hospital, and re-admitted at later time for surgery) procedures. ï?· Patients who have previously had emergency cranial surgery for traumatic brain injury rendering them eligible for inclusion in this study (regardless of whether they were included)

Design outcomes

Primary

MeasureTime frame
14-day mortalityTimepoint: 14-day mortality—

Secondary

MeasureTime frame
Return to operating theatre during follow up period ï?· Length of stay in hospital ï?· Length of stay in intensive care ï?· Glasgow Coma Score at discharge (GOS-D)Timepoint: At discharge, during 14 day follow up period—

Countries

Colombia, Ethiopia, India, Indonesia, Malaysia, Myanmar, Nigeria, Pakistan, Tanzania, United Kingdom, Zambia

Contacts

Public ContactSubhas Konar

National Institute of Mental Health And Neurosceinces

bidevidr@gmail.com09448851185

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026