Health Condition 1: N939- Abnormal uterine and vaginal bleeding, unspecified
Conditions
Interventions
Intervention1: ketamine plus levobupivacaine
combination: Patients will receive ketamine 1 mg/kg in levobupivacaine 0.25%, total volume 20 ml as subcutaneous infiltration, in and around the incision l
Sponsors
Vardhman Mahavir Medical College and Safdarjung Hospital
Eligibility
Inclusion criteria
Inclusion criteria: Patients fulfilling the American society of Anaesthesiologists (ASA) physical status I or II criteria,age from 18years to 75years,Duration of surgery less than 2 hours
Exclusion criteria
Exclusion criteria: Patients with allergy to study drugs,cardiovascular disease (such as hypertension, tachycardia, arrhythmia, congestive heart failure, and coronary artery disease,Psychiatric disorder,Neurological disease, increased intracranial pressure, seizure disorder, glaucoma, hyperthyroidism 5. Liver or renal dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cumulative pethidine requirement in 24 hTimepoint: 24 h after surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| cumulative pethidine requirement in 1, 2, 6, and 12 h time frameTimepoint: 1, 2, 6, and 12 h after surgery;Occurrence of side effects such as nausea, vomiting, sedation and hallucinationsTimepoint: 0 to 24h;Pain scores at rest and on movement postoperatively at 0, 15 and 30 min and at 1, 2, 6, 12, and 24 hTimepoint: 0, 15 and 30 min and at 1, 2, 6, 12, and 24 h after surgery;Patient satisfaction regarding postoperative analgesia at 24 hTimepoint: 24h after surgery;Time to first pethidine requirementTimepoint: 0 to 24h | — |
Countries
India
Contacts
Public ContactDr Parul Mullick
Vardhman Mahavir Medical College and Safdarjung Hospital
Outcome results
None listed