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To compare two methods for preventing propofol injection pain.

Efficacy of the Valsalva manoeuvre on propofol injection pain: A randomized controlled study

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/02/017466
Enrollment
90
Registered
2019-02-05
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Saline pretreatment, valsalva maneuvre followed by propofol injection: Assessment of pain scale and haemodynamic changes Control Intervention1: Lignocaine pretreatment, distraction foll

Sponsors

Indira Gandhi Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients of ASA physical status 1 and 2 2.Patients between 18 â?? 60 years of age of either sex 3.Patients able to comprehend and willing to participate. 4.Patients who are able to hold the sphygmomanometer up to 40 mm Hg for a period of at least 15 s 5.Patients in whom propofol is indicated for induction of anaesthesia.

Exclusion criteria

Exclusion criteria: 1.Patientâ??s refusal to participate 2.Patients with known sensitivity to lignocaine or propofol 3.Patients on concomitant analgesic or sedative medication 4.Patients with presence of infection on the dorsum of the left hand 5.Patients in whom Valsalva manoeuvre is contraindicated (e.g. raised intracranial or intraocular pressure, glaucoma, retinopathy, middle ear pathology etc) 6.Patients who are unable to hold the sphygmomanometer up to 40 mm Hg for a period of at least 15 s

Design outcomes

Primary

MeasureTime frame
incidence and severity of pain on propofol injectionTimepoint: Immediately after propofol injection

Secondary

MeasureTime frame
Haemodynamic effect of propofol administration on Valsalva manoeuvre.Timepoint: Baseline, before pretreatment, after pretreatment and after injection of propofol

Countries

India

Contacts

Public ContactFarheen Ahmed

Indira Gandhi Institute of Medical Sciences,Patna

pkdubey@hotmail.com9473191821

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026