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Comparison of two methods of cataract surgery

Evaluation of cornea friendly phaco-tip position during clear corneal phacoemulsification cataract surgery: a randomised, triple-blind, parallel group trial of phacoemulsification with bevel-up versus bevel-down - TIPS Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/02/017464
Enrollment
480
Registered
2019-02-05
Start date
Unknown
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H259- Unspecified age-related cataract

Interventions

Intervention1: Bevel-up group: The phacoemulsification of the cataract would be carried out with the bevel of the phaco probe facing upwards throughout the procedure. Control Intervention1: Bevel-down

Sponsors

Wellcome Trust DBT India Aliance
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Consecutive patients aged >18 years with immature cataract undergoing phacoemulsification at Yenepoya Medical College Hospital, Mangaluru, India and Netra jyothi charitable trust, Udupi will be selected for the study.

Exclusion criteria

Exclusion criteria: History of previous significant ocular trauma or intraocular surgery, anterior chamber depth (ACD) <2.5 mm, preoperative endothelial cell count < 1500 cells ? mm2, pseudoexfoliation syndrome, evidence of previous or current intraocular inflammation (cells/ flare/ pigment over anterior capsule or endothelium/ posterior synechiae), a preoperative fully dilated pupil <5 mm, patients on oral tamsulosine and doxazosin and corneal endothelial dystrophy. Cases with complications (suprachoroidal haemorrhage, posterior capsular rent, vitreous loss, zonular dialysis, nucleus drop, Descemet’s membrane stripping intra-operatively and post-operative endophthalmitis), those where direct chop could not be done and those lost in follow up will be excluded

Design outcomes

Primary

MeasureTime frame
Corneal endothelial cell countTimepoint: 1, 15 and 30 days post operatively

Secondary

MeasureTime frame
Central corneal thicknessTimepoint: 1, 15 and 30 days post-operatively;Intra-operative complications, if anyTimepoint: During surgery

Countries

India

Contacts

Public ContactSoujanya Kaup

Yenepoya Medical College,

drsoujanyak@gmail.com9964666647

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 28, 2026