None listed
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Indication of bilateral maxillary first premolar extraction mostly including Class IIdiv I cases and Bimaxillary protrusion cases. Erupted permanent canine s premolars and first molars. Healthy periodontal conditions with good level of oral hygiene. Positive informed consent.
Exclusion criteria
Exclusion criteria: Non compliant patient with inability to maintain proper oral hygiene. Patient with any positive history of drug intake/systemic illness which affecting bone metabolism. Patient with prior history of orthodontic treatment. Not willing for informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluate and quantify level of RANKL bone remodelling marker in GCF and rate of canine retraction with low level Laser therapy.Timepoint: 0,1hour,1 day, 21 days, 30 days, 90 days, 120 days, 180 days | — |
Secondary
| Measure | Time frame |
|---|---|
| Analysis of expression of RANKL in GCF and rate of tooth movement on subsequent Laser therapyTimepoint: 0 hour 1 hour 24 hour 1 week 21 days 1 month 3 months 4 months 6 months | — |
Countries
India
Contacts
All India Institute of medical sciences