None listed
Conditions
Interventions
None listed
Sponsors
Indian Association of Dermatologists Venereologists Leprologists
Eligibility
Inclusion criteria
Inclusion criteria: 1. Living spouse 2. Living together and eating in the same household 3. The male of the couple is engaged in spraying/ selling/ otherwise handling pesticide and the female counterpart is engaged only in household work.
Exclusion criteria
Exclusion criteria: 1. Known neurological disease 2. On treatment with cholinergic or anti-cholinergic drugs 3. Already known cases of pemphigus 4. First or second degree relative of each other before marriage 5. Handling or storing pesticides in the living area of home which might lead to exposure of pesticides to the spouse as well 6. Using protective equipment as per standardized recommendations while handling pesticides, thereby leading to negligible exposure to pesticides.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assessment of serum anti-desmoglein/ anti- muscarinic acetyl choline receptor antibodies titers as surrogate markers for pemphigus among occupationally pesticide exposed and non-exposed subjects.Timepoint: Being a cross-sectional study, the serological outcome shall be assessed at study inclusion. | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess the levels of pesticides in exposed and non exposed study participants and correlate this with anti-desmoglein/ anti-muscarinic acetyl choline receptor antibodies titers.Timepoint: No secondary outcome to assess- not applicable. | — |
Countries
India
Contacts
Public ContactDr Dipankar De
Postgraduate Institute of Medical Education and Research, Chandigarh
Outcome results
None listed