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Effect of dexmedetomedine and propofol drugs for the placement of direct laryngoscope instrument into the mouth for carrying out procedures in the voice box with the patient breathing on his own

Efficacy of Dexmedetomedine vs Propofol infusion for Tubeless Total Intravenous Anesthesia with Spontaneous Ventilation for direct laryngoscopy in patients with laryngeal tumors â?? A Randomised Controlled Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/02/017413
Enrollment
50
Registered
2019-02-04
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C323- Malignant neoplasm of laryngeal cartilage

Interventions

Intervention1: Dexmedetomedine: Loading dose of 1mg/kg followed by 0.5mg/kg/hr Intervention2: Dexmedetomedine: Intravenous 1mg/kg loading dose for 10 mins followed by 0.5mg/kg/hr intravenous infusion

Sponsors

Department of anaesthesia
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA I and II patients posted for direct laryngoscopy procedure

Exclusion criteria

Exclusion criteria: Extensive laryngeal tumors and difficult airway patients Patients on β blockers Patients who required ventilation during the procedure .

Design outcomes

Primary

MeasureTime frame
To see the Ease of the procedure using Dexmedetomedine and Propofol infusion without use of muscle relaxant with patient breathing spontaneously.Timepoint: Hemodynamics at 10 - 15 minutes of beginning of the procedure—

Secondary

MeasureTime frame
To study the hemodynamic response to direct laryngoscopy procedure for patients with laryngeal tumors. To assess Pao2 and PaCo2 levels at the end of procedure. Timepoint: Hemodynamics at 5 minutes interval till the end of the procedure. Ramsay sedation score—

Countries

India

Contacts

Public ContactDr Rachana N D

Kidwai Cancer Institute

rachanakiran84@gmail.com9886110605

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026