Health Condition 1: C569- Malignant neoplasm of unspecifiedovary
Conditions
Interventions
None listed
Sponsors
ICMR National Institute for Research in Reproductive Health
Eligibility
Inclusion criteria
Inclusion criteria: 1.Group A - Women with epithelial ovarian carcinoma as determined by histopathology/cytology aged 18-75 years 2.Group B - Age-matched healthy women with no reported symptoms gynecological problem (e.g. Ovarian cysts, uterine fibroids, RTI etc.) 3.Group C- Women with cervical disorder with morphologically normal ovaries undergoing hysterectomy along with oophorectomy
Exclusion criteria
Exclusion criteria: 1.Group A- Non-epithelial ovarian carcinoma patients, Ovarian carcinoma patient coming with a recurrence, Patients with secondary ovarian carcinoma. Retrovirus infected patients and patients taking steroids for other disorders. 2.Group C- Cystic ovaries or ovaries with benign growth or any other significant abnormality, women with uterine endometrial disorders. Women with autoimmune disorder
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| â??To qualitatively and quantitatively measure the presence of Trop2 protein in ovarian tissue and serum of patients with epithelial ovarian cancer and healthy participantsTimepoint: Since its an observational study the time point is the first patient contact. We are not calculating statistical variables related to followup. | — |
Secondary
| Measure | Time frame |
|---|---|
| To study the presence of autoantibodies and Trop2 reactive T-cells in serum of patients with ovarian cancer and healthy participantsTimepoint: Since its an observational study the time point is the first patient contact. We are not calculating statistical variables related to followup. | — |
Countries
India
Contacts
Public ContactDr Bhakti Pathak
Tata Memorial Centre
Outcome results
None listed