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Comparison of two drugs (Dexmedetomidine and Fentanyl) which are used in epidural anaesthesia for lower limb surgery.

Comparative study of Dexmedetomidine versus Fentanyl as an adjuvant to Ropivacaine (0.75%) in Epidural Anaesthesia in Lower Limb Orthopaedic Surgery.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/02/017400
Enrollment
60
Registered
2019-02-01
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: INTERVENTION DEXMEDETOMIDINE, COMPARATOR AGENT FENTANYL.: DEXMEDETOMIDINE IS NEW ALPHA ADRENERGIC AGONIST,FENTANYL IS an OPIOID Intervention2: Dexmedetomidine: It is an alpha 2 adrenerg

Sponsors

Department of Anaesthesia SSG Hospital Vadodara
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: American Society of Anaesthesiologist (ASA) Grade I and II, Patients scheduled for elective lower limb orthopaedic surgery (Unilateral or bilateral tibia and fibula surgeries like internal fixation , external fixation and plating).

Exclusion criteria

Exclusion criteria: 1. Patientsâ?? refusal/unable to give consent. 2. Patients with ASA status III and IV. 3. Patients with allergy to amide local anaesthetics . 4. Patients on α 2 antagonists, ACE inhibitors and calcium channel blockers, B blockers. 5. Patients with ischemic heart disease, heart block, Dysrhythmias. 6. Pregnant patients and Morbid obesity (BMI >35 kg/square meter). 7. Patients with Coagulopathy, Renal and liver impairment.

Design outcomes

Primary

MeasureTime frame
Time to onset of anaesthesia at T 10 dermatomal level (min)Timepoint: 7 min—

Secondary

MeasureTime frame
To document duration of effective analgesia, to find out Level of sedation,to find out adverse effects.Timepoint: 1,5,10 upto 24 hrs—

Countries

India

Contacts

Public ContactVijayalaxmi Biradar

S.S.G. Hospital, Vadodara

mgpatel111@yahoo.com9825453024

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026