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Efficacy of giving glucose orally before surgery for decrease stress response to surgery under general anesthesia

Efficacy of preoperative oral glucose loading for attenuating perioperative stress response to surgery under general anesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/02/017386
Enrollment
36
Registered
2019-02-01
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Oral glucose: Preoperatively oral Glucose 100g in 1200ml water a night before surgery and 50g on the morning of surgery in 600ml water Control Intervention1: Blood glucose, serum cortis

Sponsors

Dr Archana K P
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA physical health status 1and 2 Surgery lasting for more than or equal to 1 hour but less than or equal to 4 hours

Exclusion criteria

Exclusion criteria: Diabetes mellitus Patients on hormonal or steroid therapy Patients with endocrinological disorders Patients with BMI 30kg/m² Patients with history of gastroesophageal reflux disorders Patients on medications which impair gastrointestinal motility Laparoscopic surgeries Parturients Patients who cannot follow standard ASA fasting guidelines for any reason

Design outcomes

Primary

MeasureTime frame
Levels of serum cortisol at various intervals in perioperative periodTimepoint: Levels of serum cortisol at various intervals in perioperative period

Secondary

MeasureTime frame
Levels of blood glucose and interleukin-6 at various intervals in perioperative period Patients well being(thurst, hunger,anxiety,nausea/retching/vomiting) as assessed by 4 point scoring system at various intervals in perioperative period Timepoint: Before the induction of anesthesia, 1 hour after the start of surgery ,6 and 24 hours after surgery for blood glucose while for interleukin-6 before the induction of anesthesia and 24 hours after surgery Patients well being will be assessed using 4 point scoring system before induction of anesthesia and 1,2,6,24hours post operatively

Countries

India

Contacts

Public ContactDr Archana K P

Maulana Azad Medical College

munisha.agarwal@gmail.com9968604216

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026