Health Condition 1: E118- Type 2 diabetes mellitus with unspecified complications
Conditions
Interventions
Intervention1: B-mode Ultrasound and serum osteocalcin: A B-Mode Ultrasound shall be used to measure the Common carotid artery Intima-media thickness to assess atherosclerosis.
Serum Osteocalcin will
Sponsors
Kasturba medical college
Eligibility
Inclusion criteria
Inclusion criteria: 1)All patients above 18 years of age of both sexes. 2)Type-2 Diabetes Mellitus patients according to ADA criteria Type 2 diabetes-ADA diagnosis criteria The American Diabetes Association (ADA) criteria for the diagnosis of diabetes are any of the following (5): 1)A hemoglobin A1c (HbA1c) level of 6.5% or higher; the test should be performed in a laboratory using a method that is certified by the National Glycohemoglobin Standardization Program (NGSP) and standardized or traceable to the Diabetes Control and Complications Trial (DCCT) reference assay, or 2)A fasting plasma glucose (FPG) level of 126 mg/dL (7 mmol/L) or higher; fasting is defined as no caloric intake for at least 8 hours, or 3)A 2-hour plasma glucose level of 200 mg/dL (11.1 mmol/L) or higher during a 75-g oral glucose tolerance test (OGTT), or 4)A random plasma glucose of 200 mg/dL (11.1 mmol/L) or higher in a patient with classic symptoms of hyperglycemia (ie, polyuria, polydipsia, polyphagia, weight loss) or 5)Hyperglycemic crisis .
Exclusion criteria
Exclusion criteria: Patients with- 1)Type-1 Diabetes Mellitus 2)Bone disorders like Pagetâ??s disease, Osteomalacia. 3)Thyroid disorders 4)Parathyroid disorders 5)Acromegaly, Growth hormone deficiency 6)Chronic kidney disease, liver disease. 7)Pregnancy 8)Use of oral contraceptives, hormone replacement therapy, Vitamin K, Calcium, calcitonin, bisphosphonates, Vitamin-D, Steroids.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Association between osteocalcin levels and atherosclerosis measured by Common Carotid Intima Media thickness assessed by a B-Mode Ultrasound in Type-2 diabetes mellitus.Timepoint: 09/10/2018 to 30/07/2020 | — |
Secondary
| Measure | Time frame |
|---|---|
| Comparison between osteocalcin levels in patients with macrovascular complications and patients without any macrovascular complication.Timepoint: 09/10/208 to 30/07/2020 | — |
Countries
India
Contacts
Public ContactDr Sudha vidyasagar
Kasturba Medical college, Manipal
Outcome results
None listed