Health Condition 1: P073- Preterm [premature] newborn [other]
Conditions
Interventions
Intervention1: Addition of Human milk fortifier to Human milk at 40ml/kg/day: After meeting the inclusion criteria, addition of Human milk fortifier(Nestle HMF) to human milk at 40ml/kg/day when the n
Sponsors
Ankura hospital for women and children
Eligibility
Inclusion criteria
Inclusion criteria: They are born below 32 weeksâ?? Gestational age and weighing below 1500 gramsâ?? birth weight, AND Tolerating at least 40 mL/kg per day of enteral feeding by 7 daysâ?? postnatal age
Exclusion criteria
Exclusion criteria: Preterm infants receiving formula milk to provide >25% of total enteral feed volume Neonates with major congenital malformations Neonates with abnormal antenatal umbilical artery doppler (Increased Resistance, Absent End Diastolic Flow, Reversal of End Diastolic Flow)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time taken to regain birth weight in days in early fortification versus standard fortification group Timepoint: Time taken in days from birth to regain birth weight | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Weight gain (in grams/kg/day) from the time of enrolment until 34 weeksâ?? post menstrual age (PMA) 2. Incidence of Stage II and Stage III Necrotising enterocolitis. 3.Head growth (cms/week) 4.Length gain(cms/week) 5. Blood urea nitrogen levels,Serum calcium, phosphorous and alkaline phosphatase (ALP) levels at 34 weeksâ?? post menstrual age (PMA) as a measure of bone mineral status. 6.Weekly weight gain velocity, Head growth velocity from the time of enrolment to 34weeks PMA.Timepoint: Weekly from birth to 34 weeks post menstrual age (PMA) | — |
Countries
India
Contacts
Public ContactAparna C
Ankura hospital for women and children
Outcome results
None listed