Health Condition 1: M171- Unilateral primary osteoarthritisof knee
Conditions
Interventions
Control Intervention1: Diacerein Versus Glucosamine: Patients with newly diagnosed osteoarthritis of the knee who are to be
started on Diacerein or Glucosamine will be selected for the study. Those P
Sponsors
Dr Sruthi N
Eligibility
Inclusion criteria
Inclusion criteria: 1) Patient between 50 to 65 years with knee osteoarthritis(satisfying American college of rheumatology clinical criteria and Kellgren â?? Lawrence grade 2 or 3) 2) Patient who are willing to participate and signed in written informed consent
Exclusion criteria
Exclusion criteria: 1) Pregnancy and lactation. 2) Patients with Gastro intestinal, renal and liver diseases and diabetes. 3) Patients with acute exacerbation of OA at the time of enrolment. 4) Secondary OA and other rheumatologic diseases. 5) Patient who had undergone knee surgeries. 6) Patients who are on physical modalities from the department and patients with history of intra articular injections.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Efficacy will be evaluated primarily by the decrease in WOMAC and VAS score. Safety will be evaluated by assessing for any adverse drug reactions and causality. The number of Paracetamol tablets used and the swelling and tenderness of knee joint will also be evaluated as secondary outcomes.Timepoint: Duration of follow-up: 1 year. Follow up visits will be scheduled on 1 month, 2month, 3month and 4month. | — |
Secondary
| Measure | Time frame |
|---|---|
| The number of Paracetamol tablets used and the swelling and tenderness of knee joint will also be evaluated as secondary outcomes.Timepoint: Follow up visits will be scheduled on 1 month, 2month, 3month and 4month. | — |
Countries
India
Contacts
Public ContactDr Sruthi N
Government Medical College Kozhikode
Outcome results
None listed