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Thyroid in heart surgeries of children

A prospective randomized clinical study of preoperative thyroid hormone treatment for children undergoing surgery for congenital heart diseases

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/01/017334
Enrollment
100
Registered
2019-01-31
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: Q20-Q28- Congenital malformations of the circulatory system

Interventions

Intervention1: Dr Alok Kumar: Asst Prof (Cardiac Anaesthesia) Intervention2: TabThyroxin: Group T will recieve tab thyroxin 10 mcg/kg orally one day before surgery and 10 mcg/kg everyday through feedi

Sponsors

Army Hospital Research and Referral
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Paediatric patients ( <10 kg) with congenital heart diseases undergoing on pump cardiac surgery at Army Hospital R&R, for various indications will be included in the study.

Exclusion criteria

Exclusion criteria: Patients having any association with syndrome, patients with dysarhythmias, patient on preoperative inotropes will be excluded from the study.

Design outcomes

Primary

MeasureTime frame
LV Cardiac Output by echocardiographyTimepoint: 24 hrs and 72 hrs after surgery

Secondary

MeasureTime frame
ICU measurements will include duration of ICU stay, incidence of Low cardiac output syndrome, postoperative ICU stay, Duration of mechanical ventilation, Incidence of arrhythmia, any thoracic epidural related adverse event, and renal replacement therapy given if any. Separated serum will be assayed for estimation of serum T3 and free thyroxine (T4) and thyrotropin releasing hormone (TSH) . Timepoint: Blood samples for T3,T4 and TSH will be collected preoperatively (T0), 24-hr (T1) and three (T2) days after surgery. ICU data will be collected till the patient is discharged from the ICU or dies whichever is earlier.

Countries

India

Contacts

Public ContactDr Alok Kumar

Army Hospital Research and Referral

mipayal07@gmail.com8146044104

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026