Study comparing the effect of pain relief provided by one combination of drug(Ketofol) with that of the other(Etofen)

A Randomised Controlled Trial Comparing the procedural sedative and analgesic actions of ketofol and etofen during procedures in the emergency department

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/01/017329

Enrollment

110

Registered

2019-01-31

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: T14-T14- Injury of unspecified body region

Interventions

Control Intervention1: 1)Hypersensitivity to Ketofol or Etofen 2)Age less than 18 years 3)ASA 3 and 4 : Combination of etomidate and fentanyl. Intravenous administration Titrating dosage of etomidate(

Eligibility

Inclusion criteria

Inclusion criteria: All patients who decided to receive PSA for procedures and ASA physical status 1 or 2

Exclusion criteria

Exclusion criteria: 1)Hypersensitivity to Ketofol or Etofen 2)Age less than 18 years 3)ASA 3 and 4

Design outcomes

Primary

Measure	Time frame
1) Pain severity (visual analogue scale) 2) Adequacy of sedation and analgesia between two groups (Modified Ramsay Sedation Score) 3) Incidence of airway adverse events Timepoint: 5 minutes	—

Secondary

Measure	Time frame
To compare the other adverse effects between two groups (additional drug needed, sedation duration, sedation level and patient pain and physicians satisfaction scores) 2) To determine the alterations in hemodynamic changes between two groups Timepoint: 5min	—

Countries

India

Contacts

Public ContactSreekanth wodeyar

Bangalore Baptist hospital

wodeyar.sree@gmail.com7349617950

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026