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nausea and vomiting after surgery

Comparison of dexamethasone versus ondansetron following preoperative administration of intravenous crystalloid for prophylaxis of postoperative nausea and vomiting in patients of laparoscopic cholecystectomy

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
CTRI
Registry ID
CTRI/2019/01/017295
Enrollment
50
Registered
2019-01-28
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K00-K95- Diseases of the digestive system

Interventions

Control Intervention1: 8 mg Dexamethasone & 4 mg Ondansetron: 10 ml/kg of intravenous crystalloid (RL) is given over a period of 1 hour before surgery and 8 mg of dexamethasone is given before inducti

Sponsors

University college of medical sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: American Society of Anaesthesiologist(ASA) physical grade I and II Non Smoker Scheduled for Laparoscopic Cholecystectomy

Exclusion criteria

Exclusion criteria: 1.Patients who had received corticosteroids, opioids, antiemetics within last 24 hrs 2.Patients havinhg H/O - Hypertension, diabetes mellitus, thyroid disorder, hepatic and renal disorder 3. Patients having H/O motion sickness 4. Lactating or menstruating patients

Design outcomes

Secondary

MeasureTime frame
1.Requirements of rescue antiemetic in two groups 2.Postoperative pain score and requirements of rescue analgesic in two groupsTimepoint: 1.Requirements of rescue antiemetic in two groups within 24 hours 2.Postoperative pain score and requirements of rescue analgesic in two groups within 24 hours

Primary

MeasureTime frame
Occurence and severity of PONV in two groupsTimepoint: Occurence and severity of PONV in two groups within 24 hrs

Countries

India

Contacts

Public ContactK LALCHHANCHHUAHI

University College of Medical Sciences and Guru Teg Bahadur Hospital

mahendramohit@yahoo.com9868399709

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026