Health Condition 1: -
Conditions
Interventions
Intervention1: Dexmedetomidine(0.25 mcg/kg over 4 minutes by IV route followed by 0.4mcg/kg/hour infusion: This Group - would receive bolus dose of dexmedetomidine 0.25 mcg/kg (labelled as drug 1, v
Sponsors
PGIMER Chandigarh
Eligibility
Inclusion criteria
Inclusion criteria: 1. American Society of Anesthesiologists physical status I or II 2. Age of 1 to 5 years 3. Either gender 4. Estimated operation time of 5. Written informed consent of parents to undergo the therapeutic regimen
Exclusion criteria
Exclusion criteria: 1. Renal dysfunction (serum creatinine > 1.2mg/dl) 2. Liver dysfunction (liver enzymes twice the normal range or higher) 3. Allergy to study medication 4. Participants parents devoid of postoperative telephone access
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to remove the airway device (from the end of surgery till extubation)Timepoint: Time to remove the airway device (from the end of surgery till extubation) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Spontaneous breathing recovery time (from the end of drug infusion to recovery of spontaneous breathing) 2. Degree of sedation: 3. Hemodynamic indices: 4. Anaesthesia time (from anesthesia induction to extubation); and operative time (from skin incision to the end of suturing) will be noted 5. Intraoperative MAC requirement will be noted every 10 mins 6. Duration of PACU stay Timepoint: Every 10 minutes postoperatively till discharge from pacu area | — |
Countries
India
Contacts
Public ContactShyam Charan Meena
PGIMER Chandigarh
Outcome results
None listed