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Neem for oral lichen planus patients.

Evaluation of the efficacy of topical neem extract in the management of Oral lichen planus.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/01/017246
Enrollment
80
Registered
2019-01-25
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: D899- Disorder involving the immune mechanism, unspecified

Interventions

Intervention1: Clobetasole propionate and neem leaves extract mouthwash.: Clobetasole (0.05%) mouthwash and neem leaves extract mouthwash (5-20%)are give to symptomatic oral lichen planus patients to

Sponsors

Dr Ashita Kalaskar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Symptomatic Patients with any clinical types and manifestations of OLP and those confirmed histopathologically will be included in the study. 2.Patients who have discontinued previous treatment for OLP for last six months.

Exclusion criteria

Exclusion criteria: 1.Patients younger than 16 years old. 2.Patients with skin lesions. 3.Patients with non symptomatic OLP lesions 4.Patients with lesions showing malignant or dysplasic changes. 5.Patients undergoing any other treatment for oral lichen planus. Pregnant and nursing woman. Patients having systemic problems or under any medications for the same. Patients having habit of chewing tobacco and betelnut or smoking

Design outcomes

Primary

MeasureTime frame
Burning sensation will be evaluated by visual analog scale. The severity of lesions on each side will be evaluated by Thongprasom criteria.Timepoint: 1st day, 3rd day, 7th day, 2nd week, 3rd week, 4th week, 2nd month and 3rd month

Secondary

MeasureTime frame
Acceptability of neem mouthwash. Total duration required to decrease the symptoms. Recurrence of the lesions in two months follow-up. Clinical improvement.Adverse effects if any.Timepoint: 1st day, 3rd day, 7th day, 2nd week, 3rd week, 4th week, 2nd month, 3rd month.

Countries

India

Contacts

Public ContactAshita Kalaskar

Government Dental College and Hospital, Nagpur

kalaskarashita@gmail.com8550928585

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026