FindTrial
Sign In

TO COMPARE 2 GROUPS IN WHICH BOTH TAKES TAB.DESIROX BUT ONE GROUP WILL ADDITIONAL TAKE INJ.DESFERRAL AFTER TAKING MONTHLY BLOOD TRANSFUSION

TO ASSESS THE EFFICACY OF IRON CHELATORS : DAILY ORAL DEFERASIROX V/S COMBINATION OF DAILY ORAL DEFERASIROX + INTERMITTENT INJECTABLE DEFEROXAMINE IN REDUCING SERUM FERRITIN LEVEL IN THALASSEMIA MAJOR PATIENT

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/01/017229
Enrollment
60
Registered
2019-01-24
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: D561- Beta thalassemia

Interventions

Intervention1: group B: tab.desirox via oral route in 20-40mg/k/day with monthly blood transfusion along with intermittent(when pt come for blood transfusion then and thrn only) inj.desferral in 40-60

Sponsors

TANMAY VAGH
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: age-3 years to 18 years serum ferritin level-1000 to 5000mg/dl

Exclusion criteria

Exclusion criteria: Pt Pt >18years Renal failure Cataract Ototoxicity HIV positive/ Hepatitis B positive/Hepatitis C positive Av block or pt with cardiac arrathymias Severe allergy to the drugs Pt with other associated congenital malfirmations

Design outcomes

Primary

MeasureTime frame
To measure consecutive serum ferritin level in group A whom dail oral iron chelator with monthly blood transfusion in Paediatric ward sir T hospital Bhavnagar,GujaratTimepoint: Total 6 month duration.—

Secondary

MeasureTime frame
To measure consecutive serum ferritin level in patient with β Thalassemia major every 2 month with ongoing dosage of iron chelators in both study group A & B admitted in Paediatric ward sir T hospital Bhavnagar,GujaratTimepoint: 2 month—

Countries

India

Contacts

Public ContactTANMAY VAGH

GOVT.MEDICAL COLLEGE & SIR T HOSPITAL,BHAVNAGAR

drmehulgosai78@gmail.com9426804255

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026